analysis software / reporting / for mass spectrometry / for the pharmaceutical industry
BioPharma Compass 3.0 Bruker Daltonics Inc.

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Characteristics

  • Function:

    analysis, reporting

  • Application domain:

    for mass spectrometry, for the pharmaceutical industry

Description

BioPharma Compass 3.0 – Accelerate Biopharmaceutical Analysis
BioPharma Compass 3.0 enables the routine analysis of biopharmaceuticals offering dedicated LC and MS workflows from automated measurements to report generation. MS assays that are playing an increasingly important role in biopharmaceutical development - such as verification of protein sequences and quantification of product and process related heterogeneities - are optimized to reduce the samples-to-report time.

These measurements can be carried out at the intact, domain (subunits) or peptide level using MS only or MS/MS for top-down and bottom-up analysis. Both high resolution ESI-QTOF and MALDI-TOF data can be employed for these analyses. Dedicated similarity scores are the basis for an automatic result assessment, and reports utilize color coding of results and charts for rapid reviewing. Butterfly plots enable visual dataset comparisons.

Butterfly plot showing a deconvoluted spectrum from a test sample and a reference.
Taking full advantage of the benefits of Bruker’s ultra-high resolution QTOF, the maXis II, and the market-leading MALDI-TOF/TOF platforms, BioPharma Compass 3.0 further extends Bruker’s expertise in biopharmaceutical characterization. It provides users with customizable workflows for common biopharmaceutical applications. This powerful suite of tools automates the processes of acquiring, analyzing and reporting data. Laboratories under 21 CFR Part 11 compliance will benefit from the regulatory options, including leading data security features.