Mechanical milling remains an important formulation step in the pharmaceutical industry, typically best suited to delivering uniform particle sizes above 20 microns. Whether your drug is in development, starting clinical trials, or ready for commercial production, FPS mills can deliver a mechanical milling solution that consistently achieves this, enhancing particle homogeneity, distribution uniformity, compound bioavailability and solubility.
From ensuring proper blend uniformity to optimizing release profiles, our mechanical milling operations provide superior pharmaceutical results.
FPS Mechanical Mills available are: PinMill-100, PinMill-200, HammerMill-100 and HammerMill-200.
Hammer Mill– High-throughput hammer mills can help you achieve a variety of particle size-reduction requirements; including delumping, milling to a specific particle range, and fine grinding applications. For pharmaceutical milling, xxxx employs hammers alongside interchangeable screen sizes, for greater control over the final particle size.
Pin Mill– This mill provides a uniform particle size without the need for screens. Particle size reduction takes place between two plates containing pins — one stationary and one rotating. Mechanical milling with a pin design can provide a smaller particle size than a hammer mill.
The size reduction of the product is considered function of the following parameters:
the product being processed, with its chemical and physical properties;
the rotating speed;
the product feed rate into the milling chamber, that defines the quantity of product inside the milling chamber;
the process temperature.