Automatic immunoassay analyzer Zenit RA

for clinical diagnosticchemiluminescencebenchtop

A.A thermo-regulated carousel set at 37°C with 90 positions for disposable cuvettes. A spectrophotometer for measuring absorbance in certain immunoassay reactions is incorporated into the carousel B.A pipetting arm that pipettes both reagents and samples C.A sample tray with 64 positions for samples, calibrators and controls D.A refrigerated reagent compartment, consisting of 15 rails containing the immunoassay reagent racks. The reagent cartridges are stored in the refrigerated reagent compartment between 12 and 15°C while the analyzer is operating, and between 8 and 10°C in standby mode E.An automatic cuvette loader, holding 960cuvettes at a time (pre-formed as a cube) F.Two barcode readers (one located on the front face of the analyzer, the other integrated into the reagent compartment) identify samples, ancillary reagents and reagent cartridges G.Four washers for washing magnetic particles H.A luminometer measuring luminescence in immunoassay reactions (directly in the cuvette) AN INNOVATIVE OPERATING PRINCIPLE CLIA (CHEMILUMINESCENCE ENZYME IMMUNOASSAY) BASED TECNOLOGY The assay is based on a two-step indirect chemiluminescent method that generates quantitative results. This particular technique uses autoantigen-coated magnetic particles as solid phase and an antibody labeled with a dimethyl acridinium ester (DMAE) as detection marker. The use of high quality antigens and large coated surfaces provides excellent sensitivity in Zenit RA immunoassays. 1.In the first incubation phase, specific autoantibodies present either in the sample, calibrators or controls bind to the immobilized antigen