The Randox methodology was compared against other commercially available methods and the Randox cholinesterase (butyryl) reagent showed a correlation coefficient of r=0.9959
Excellent stability
Stable for 6 weeks when stored at +2 to +8°C
Other features of the Cholinesterase (Butyryl) (BCHE / BuCHE) reagent
Colorimetric method
Lyophilised reagents
Correlation coefficient of r=0.99 when compared with another commercially available method
Stable for 6 weeks when stored at +2 to +8°C
Measuring range 455-28722U/l
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What is the Cholinesterase (Butyryl) (BCHE / BuCHE) assay used for?
What is cholinesterase (butyryl)?
Cholinesterase (butyryl) (BCHE / BuCHE), also known as pseudocholinesterase, is a protein coding gene and is a serine hydrolase synthesised in the liver and is responsible for catalysing the hydrolysis of numerous choline esters. It can be found in the liver, intestinal mucosa, plasma, pancreas and the white matter of the central nervous system of mammals.
The Randox Cholinesterase (butyryl) reagent is used for the quantitative in vitro determination of BCHE in serum and plasma. BCHE can be used to diagnose cholinesterase (butyryl) deficiency and curariform drugs toxicity.
The Randox Cholinesterase (butyryl) reagent can also be used as a diagnostic and therapeutic marker for Alzheimer’s disease as BCHE activity progressively increases in patients with Alzheimer’s disease whereas acetylcholinesterase activity remains the same or declines.