Clinical chemistry assay kit LD401

lactate dehydrogenasebiochemistry

The Randox lactate dehydrogenase (LDH) P-L assay utilises the UV method. Applications are available detailing instrument-specific settings for the convenient use of the Randox assay on a wide range of clinical chemistry analysers. Liquid ready-to-use and lyophilised reagents available offering choice and flexibility. Randox Lactate Dehydrogenase P-L (UV) UV method Liquid and lyophilised reagents available Stable to expiry at 2-8°C What is Lactate Dehydrogenase assay used for? Lactate dehydrogenase (LD) catalyses the interconversion of lactic acid and pyruvic acid. The enzyme is composed of 4 peptide chains and exists in 5 isomeric forms. LD is widely distributed throughout the body, and the highest concentrations are found in the liver, heart and skeletal muscle. LD activity is significantly elevated during myocardial infarction. Maximum levels are reached 24 to 48 hours after the onset of chest pain and may remain elevated for 7 to 12 days post infarction. Increases in LD activity are also associated with other pathological conditions including liver disease, progressive muscular dystrophy, megaloblastic and pernicious anaemia.