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antibodies / for breast cancer / progesterone / immunohistochemistry
antibodies
Novocastra PA0312

Antigen Background The human progesterone receptor (PR) is expressed as two isoforms, PRA (94 kD) and PRB (114 kD), which function as ligand-activated transcription factors. These two isoforms are transcribed from distinct estrogen receptor ...

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Leica Biosystems
breast cancer reagents / antibodies / immunohistochemistry
breast cancer reagents
Novocastra Cytokeratin 5

Antigen Background Cytokeratins are a large family of cytoskeletal proteins found in epithelial cells. They are coordinately synthesized in pairs so that at least one member of each family is expressed in each epithelial cell. Cytokeratins ...

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Leica Biosystems
breast cancer reagents / for tissue cultures / monoclonal antibodies / for antigens
breast cancer reagents
Novocastra Cytokeratin 7

Antigen Background Cytokeratins are intermediate filament proteins present in epithelial cells. They are expressed in a tissue-specific manner in normal organs and the tumors that arise from them. Cytokeratin 7 belongs to the neutral ...

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Leica Biosystems
breast cancer reagents / pathology / monoclonal antibodies / for antigens
breast cancer reagents
Novocastra Cytokeratin 14

Antigen Background Cytokeratins 14 and 5 are useful to distinguish stratified epithelial cell types from simple epithelial cell types. Cytokeratin 14 has been reported to be expressed in neoplasms of squamous cell origin. Product ...

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Leica Biosystems
breast cancer reagents / for tissue cultures / pathology / monoclonal antibodies
breast cancer reagents
Novocastra Cytokeratin 20

Antigen Background Cytokeratin 20 has been demonstrated to be almost entirely confined to the gastric and intestinal epithelium, urothelium and Merkel cells of the skin. Cytokeratin 20 is less acidic than other type I cytokeratins ...

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Leica Biosystems
breast cancer reagents / monoclonal antibodies / for antigens / tissue
breast cancer reagents
Novocastra E-Cadherin

Antigen Background E-cadherin is a Ca2+-dependent, transmembrane cell adhesion molecule. It plays an important role in the growth, development and the intercellular adhesion of epithelial cells. Most tumors have an abnormal architecture ...

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Leica Biosystems
breast cancer reagents / monoclonal antibodies / for antigens / tissue
breast cancer reagents
Novocastra Estrogen Receptor

... antibodies to ER has allowed the determination of receptor status of breast tumors to be carried out in routine histopathology laboratories. Product Specific Information Clone 6F11 is raised to the full length alpha ...

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Leica Biosystems
breast cancer reagents / monoclonal antibodies / for antigens / tissue
breast cancer reagents
Novocastra Fluid Protein-15

Antigen Background Gross cystic disease of the breast is a benign premenopausal disorder in which cysts are a predominant pathological lesion. These cysts appear to be formed from excessive apocrine cystic secretions. This fluid is ...

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Leica Biosystems
tissue culture reagents / pathology / for breast cancer / monoclonal antibodies
tissue culture reagents
Novocastra Ki67

The Ki67 antigen is a nuclear protein which is expressed in all active parts of the cell cycle (G1, S, G2 and mitosis) but is absent in resting cells (G0). In contrast to many other cell cycle-associated proteins, the Ki67 antigen is ...

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Leica Biosystems
breast cancer reagents / monoclonal antibodies / for antigens / cell
breast cancer reagents
Novocastra Multi-Cytokeratin (AE1,AE3)

Antigen Background Keratins are a family of water insoluble proteins of 40 to 70 kD. These proteins form tonofilaments, a class of intermediate filament, in epidermis as well as in almost all other epithelia. The process of normal epidermal ...

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Leica Biosystems