biochemistry reagent / serum / alkaline phosphatase / kinetic
This reagent is intended for in vitro quantitative determination of Al kaline
Phosphatase in serum or plasma.
- DGKC – SCE recommended procedure with DEA buffer
- Linear upto 900 U/L
- Working reagent stable upto 7 days at 2-8OC
Alkaline phosphatase is widely distributed throughout the body, but clinically
important one for diagnostic reasons are in bone, liver, placenta & intestine.
Growing bone is associated with the release of ALP and so in childhood the level
of ALP is around 3 times of that of adult. During pregnancy in 2nd & 3rd trimester
the enzyme rises considerably due to placenta releasing ALP. It can be used to
examine placental function.
Elevated levels are seen in bone diseases, e.g. pagets disease, rickets, osteoblastic
metastatic & in obstructive disease of biliary tract.
Decreased levels are rarely seen. e.g. in Vitamin A resistant rickets.
Kinetic determination of ALP according to the following reaction