1-channel infusion pump

continuousimplantableosmotic

ALZET pumps are available in a variety of sizes, durations and flow rates to meet a wide range of research needs. While the pumping rate of each model is fixed at manufacture, the dose of agent delivered can be adjusted by varying the concentration of agent with which each pump is filled. Provided the animal is of sufficient size, multiple pumps may be implanted simultaneously to achieve higher delivery rates than are attainable with a single pump. For more prolonged delivery, pumps may be serially implanted with no ill effects. • Animal size: refer to our guidelines for pump implantation based upon animal size • Route of compound administration for the desired target tissue and response • Desired delivery rate • Preferred duration of administration • Compound characteristics* (solubility, cost) • Dose • Ambient Temperature & Osmolality (relevant to use in heterotherms or in vitro only) ALZET pumps can be implanted subcutaneously or intraperitoneally following the animal size guidelines below. ALZET pumps may also be connected to a catheter to deliver the pump contents directly into the venous or arterial systems, the brain, or into any organ or tissue. We recommend use of the smallest size pump allowable for the solubility of the agent and duration of the experiment. The pumps have been used in animals across the age spectrum, and in many different species. Following are specific tips on using ALZET pumps in a few specific animal models: Neonates Nude mice Species or applications in heterothermic animals Species or application at osmolalities other than mammalian