Liquid cleaner CIDEZYME BIOCLEAN™

3780 mlenzymeenzymatic

Overview

CIDEZYME BIOCLEAN™ is an enzymatic detergent formulated to address biofilm removal during manual cleaning of flexible endoscopes and medical devices. Manual cleaning is the essential first step in reprocessing because biofilm within internal channels can shield microorganisms from subsequent high-level disinfection or sterilization. When used according to the Instructions for Use (IFU), CIDEZYME BIOCLEAN™ supports physical removal of biofilm from channels and surfaces.

Key Product Highlights

• First ASP detergent with evidence aligned to ISO 15883-5 cleaning acceptance criteria
• Specifically formulated to remove biofilm from flexible endoscope lumens
• Defined cleaning parameters (time, temperature, mechanical action) for reproducible results when used per IFU
• Supports effective manual cleaning as the basis for high-level disinfection and sterilization

What Makes CIDEZYME BIOCLEAN™ Different

ISO-Aligned Biofilm Removal
CIDEZYME BIOCLEAN™ targets a critical risk in endoscope reprocessing by delivering demonstrable biofilm disruption and removal beyond surface cleaning.

• Aligned with ISO 15883-5 cleaning acceptance criteria
• Evidence of effective biofilm disruption and extraction from internal channels

Defined & Reproducible Cleaning Process
The product is designed to move manual cleaning from assumption to a controlled, repeatable procedure.

• Operates with defined parameters: time, temperature and mechanical flow
• Enables standardization across users and facilities to reduce variability

Efficient & Practical Use Conditions
Formulated for integration into clinical workflows without added complexity.

• Contact time: 3-minute soak + 5-minute flush (under defined conditions)
• Working concentration: 8 mL/L at 30°C (highly concentrated)
• Use with a flushing aid delivering a minimum flow of 1000 mL/min through channels

Advanced Formulation Performance
Performance derives from a formulation optimized for real-world channel soils and biofilm.

• Unique enzyme-surfactant synergy to disrupt biofilm matrix
• Low-foaming for improved usability and residue removal

Safe, Compatible & Sustainable
Balances cleaning performance with material compatibility and environmental considerations.

• Demonstrated superior material compatibility compared with some leading detergents
• Readily biodegradable formulation per OECD310

Order Code (packaging)

Product Name | Product Number | Packaging
CIDEZYME BIOCLEAN™ | 88301 | 1 Gallon bottle (3.78 L); Case: 4 × 1 gallon + 1 pump

Frequently Asked Questions (selected)

• Why is biofilm found in endoscopes, and why is it a concern during reprocessing? Biofilm forms within complex internal channels that are difficult to access and fully clean. It increases microbial resistance to high-level disinfection and raises the risk of patient-to-patient transmission.
• What is the mechanism of action of CIDEZYME BIOCLEAN™? The formulation combines a targeted enzyme with surfactants to disrupt the extracellular polymeric substances (EPS) matrix of biofilms. Under defined conditions (≥1000 mL/min flow, 30°C, 5-minute flush), chemical and mechanical action enable effective removal meeting ISO 15883-5:2021 criteria.
• Does the mild pH affect material compatibility? No. Mild pH detergents are generally compatible with endoscope materials. CIDEZYME BIOCLEAN™ has shown excellent material compatibility and corrosion inhibition, outperforming some neutral pH competitors.
• Can CIDEZYME BIOCLEAN™ be used with existing flushing aid devices? Yes, provided the device delivers the minimum required flow (1000 mL/min) and does not require authentication for a specific detergent.
• How does CIDEZYME BIOCLEAN™ achieve better cleaning than multi-enzymatic detergents? Superior results are achieved through the synergy of formulated chemistry and defined mechanical parameters rather than enzyme count alone.
• Why are two contact times specified? A 3-minute soak removes external organic soils; a subsequent 5-minute flushing step targets biofilm within channels under defined flow and temperature conditions.

Specifications / Technical details

• Trade name: CIDEZYME BIOCLEAN™
• Intended use: Manual cleaning of flexible endoscopes and medical devices to remove organic soil and disrupt biofilm prior to high-level disinfection or sterilization
• ISO alignment: Cleaning evidence aligned to ISO 15883-5 (biofilm removal acceptance criteria)
• Contact times: 3-minute soak + 5-minute flush (under defined conditions)
• Working concentration: 8 mL/L @ 30°C (highly concentrated)
• Required mechanical action: Flushing with minimum flow 1000 mL/min for channel biofilm removal
• Formulation: Enzymatic detergent with surfactants; low-foaming
• Material compatibility: Superior compatibility vs. some leading detergents; mild pH and corrosion inhibition demonstrated
• Biodegradability: Readily biodegradable per OECD310 standard
• Packaging example: 1 Gallon bottle (3.78 L); Case: 4 × 1 gallon + 1 pump
• Manufacturer/Brand: ASP (Advanced Sterilization Products)