Solution reagent kit QuantideX® minor

laboratoryfor researchfor qPCR

The QuantideX® qPCR BCR-ABL minor Kit (RUO) is a clinical research tool enabling ultra-sensitive and precise detection of BCR-ABL1 minor fusion transcripts (e1a2) from whole blood specimens. Building on the simple workflow and best-in-class sensitivity established with the FDA-cleared QuantideX® qPCR BCR-ABL IS Kit, the minor Kit allows labs and clinical researchers to examine the biology of disease for this very rare but distinct leukemic variant with unprecedented ease. Features & Benefits The QuantideX qPCR BCR-ABL minor Kit (RUO) delivers high performance through unmatched sensitivity and optimized laboratory efficiency. Reduced Complexity Ease-of-data analysis and reporting: Leverages the QuantideX® qPCR BCR-ABL IS Kit workflow concept for streamlined implementation QuantideX qPCR Reporter provides automated calculation of BCR-ABL1/ABL1 % ratio and eliminates the need for manual calculation Optimized Workflow Valuable operator hands-on time has been significantly reduced through: Multiplexed design amplifies and detects both fusion and control gene in the same reaction All-inclusive reagents sourced and quality controlled together from a single vendor Pre-mixed reagents allow fewer pipetting steps in mastermix preparation Quality Performance Detecting BCR-ABL1 minor transcripts robustly and reliably with a highly sensitive assay: Ultra-sensitive Limit of Detection (LOD): Log reduction of 4.61 (0.0025% ratio) Increased analytical sensitivity without compromising analytical specificity: incorporates Limit of Blank (LOB) to prevent miscalling of non-leukemic low positives Armored RNA®-based standards provide true RNA quantification