Anti-CCP2 test kit FHCCP100
for rheumatoid arthritisclinicalserum

anti-CCP2 test kit
anti-CCP2 test kit
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Characteristics

Applications
for rheumatoid arthritis
Tested parameter
anti-CCP2
Sample type
clinical, serum, plasma
Analysis mode
immunoassay, ELISA, turbidimetric
Specificity

90 %

Description

The measurement of anti-CCP antibodies has become the method of choice in the accurate diagnosis of Rheumatoid Arthritis. Anti-CCP2 positivity can predict future development of RA in both asymptomatic individuals and in patients with undifferentiated arthritis. Traditionally Anti-CCP testing has been performed using ELISA assays or on closed mainframe immunoassay analysers. Now for the first time Anti-CCP testing can be performed on open chemistry systems using the new Axis-Shield Clinical Chemistry Anti-CCP kit. Proven, reliable CCP2 technology CE-marked Low Total Imprecision Intended Use The Axis-Shield Anti-CCP test is a semi-quantitative assay for the detection of autoantibodies specific to cyclic citrullinated peptide (CCP) in either human serum or plasma specimens. Detection of anti-CCP antibodies is used as an aid in the diagnosis of Rheumatoid Arthritis (RA), and should be used in conjunction with other clinical information. Autoantibody levels represent one parameter in a multi-criterion diagnostic process, encompassing both clinical and laboratory-based assessments. Assay Principle The determination of anti-CCP antibodies is based on a specific turbidimetric reaction which occurs between the antibodies present in the serum/plasma of patients affected by Rheumatoid Arthritis (RA) and highly purified synthetic cyclic citrullinated peptide coated on the surface of latex microparticles. Reaction occurs under optimal pH conditions and in the presence of an accelerator. The turbidity of the immune complex is proportional to the concentration of the analyte in the examined sample.

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