Xenograft bone substitute GenMatrix® - DBM

for dental sugerymalleable

Product description
GenMatrix® is a demineralized bone matrix (DBM) derived from bovine cancellous bone, indicated as an osteoconductive filling material for non-structural alveolar and surgical bone defects in dental applications. Produced by controlled physico-chemical demineralization and lyophilization, the material preserves the organic matrix and natural three-dimensional porous architecture, yielding a predominantly organic, acellular, biocompatible and non-pyrogenic biomaterial.

Applicability
GenMatrix® is intended to expand clinical options in dental regenerative procedures, offering predictable handling and biological performance. Main clinical uses include:

• Filling of post-extraction sockets
• Treatment of non-structural surgical bone defects
• Filling of peri-implant gaps

Prior to placement hydrate the material in sterile physiological solution or the patient’s blood. The hydrated matrix becomes more homogeneous, translucent and flexible, facilitating adaptation to the defect. Prepare the surgical site appropriately (remove fibrous/necrotic tissue; decortication when indicated) and place without excessive compaction to preserve porosity. Use of a biocompatible membrane is recommended when indicated.

Advantages
Key differentiators of GenMatrix® include:

• Preserved natural porous architecture that favors rapid hydration, neovascularization and migration of osteoprogenitor cells
• Progressive integration and replacement by vital bone through osteoconduction
• Easy handling: becomes flexible after hydration for precise molding and stabilization
• Avoids need for autogenous bone harvesting, reducing morbidity and operative time
• Clinical versatility: usable alone or combined with autografts or cell concentrates
• Backed by Baumer’s expertise in biomaterials

Characteristics / technical specifications

• Brand: Baumer
• Commercial name: GenMatrix - DBM
• Biological origin: bovine cancellous bone (decellularized and demineralized matrix)
• Primary use: osteoconductive filling material for non-structural bone defects in dental applications
• Indications: post-extraction socket filling, non-structural surgical bone defects, peri-implant gap filling
• Patient population: indicated for patients with bone maturity
• Preparation: hydrate in sterile physiological solution or patient’s blood prior to placement
• Handling: becomes homogeneous, translucent and flexible after hydration
• Placement guidance: position without excessive compaction to preserve porosity; use membrane when indicated
• Compatibility: can be used alone or combined with autogenous grafts or cell concentrates
• Intended benefits: osteoconduction, supports neovascularization and osteoprogenitor cell migration, progressive replacement by vital bone