OverviewSphera™ is a lyobead production system using discrete droplet dispensing to generate stable, single‑unit Lyobeads for reagents and assays. The system supports precise, high‑speed, non‑contact dispensing across R&D and production scales.
Features- Single‑drop volumes: 2 µL – 30 µL
- Volume precision: <3% CV
- High‑speed, non‑contact pneumatic dispensing
- Bulk dispense scalable from R&D to production
- Printing modes: Step-and-Repeat and On-the-Fly
- Reduces cold‑chain logistics and associated costs
- Lyobeads are thermally stable with extended shelf life
- Lower contamination risk via single‑unit reconstitution
Applications- Enzymes
- Buffers
- Chromophores
- Probiotics
- Vaccines
- Calibrators
- PCR assays
- Antibodies
- Diagnostic reagents
- Magnetic and fluorescent particles
Options & Technology- Pneumatic BioJet™: high‑speed micro solenoid valve with adaptive pneumatic pump
- High‑speed non‑contact dispensing (Bulk Dispense option available)
- Printing modes: Step-and-Repeat and On-the-Fly
- Dispensing tip geometries and orifice sizes to optimize drop volume and morphology for ideal Lyobead spheres
- Throughput estimates: Single tip ≈ 7,000–10,000 beads/hr; Four tips ≈ 28,000–40,000 beads/hr
Technical specifications- Commercial name: Sphera™
- Brand: BioDot
- Volume range (single drop): 2 µL – 30 µL
- Volume precision: <3% CV
- Dispensing mode: High‑speed, non‑contact pneumatic dispensing
- Estimated production throughput: Single tip ~7,000–10,000 beads/hr; Four tips ~28,000–40,000 beads/hr
- Dispensing tips: Stainless Steel or PEEK
- Stainless Steel tip orifice sizes: 508 µm; 762 µm; 1016 µm
- PEEK tip orifice sizes: 762 µm; 1016 µm
- Printing modes supported: Step-and-Repeat; On-the-Fly
- Use case scalability: R&D to production environments
- Lyobead attributes: thermally stable, long shelf life, reduced contamination risk, single‑unit reconstitution