GastroPanel® test is a patient friendly, non-invasive, simple blood test for diagnosis of the function and structure of stomach mucosa. GastroPanel test is intended as the first-line diagnostic test of the patients suffering from dyspepsia. It is a particularly useful tool for general practitioners and occupational health doctors, because the results can be used to evaluate the need for further investigations (usually gastroscopy).
GastroPanel test detects four biomarkers. Three of these biomarkers are secreted by the cells in gastric mucosa: pepsinogen I (PGI), pepsinogen II (PGII) and gastrin-17 (G-17). These are complemented by Helicobacter pylori antibody measurement. This complete panel of all four biomarkers provides a more comprehensive profile of the gastric mucosa than could be achieved by using any of these as stand-alone biomarkers.
GastroPanel test identifies Helicobacter pylori infection and indicates whether chronic infection has progressed to atrophic gastritis. GastroPanel test also accurately confirms abnormalities in acid output. Since Helicobacter pylori infection and atrophic gastritis are the most important risk factors for stomach cancer, GastroPanel test can also be used for screening of asymptomatic subjects for the risks of gastric cancer.
GastroPanel test kits are based on the ELISA (enzyme-linked immunosorbent assay) principle and hence can be used with a variety of analysis equipment (manual or automated). The latest kits feature unified reagents and reaction conditions, making them even more accessible.