Evaporative Light-scattering Detector
Biotage® ELSD (evaporative light-scattering detector) is a universal detector designed for use with Isolera™ flash purification systems when purifying organic compounds that are undetectable UV or visible light.
Flash chromatography with detection and fractionation is now possible when purifying carbohydrates, steroids, lipids, terpenes and other UV-transparent compounds. The ELSD-A120 is the replacement to the popular ELSD-1080 universal detector designed for use with Isolera™ flash purification systems when purifying organic compounds that are undetectable with UV or visible light.
Organic compounds have different chemical and physical properties and they impact detection, even with an ELSD. Biotage® ELSD-A120 provides intelligent method design which enables the chemist to independently set nebulizer and evaporator temperatures for a particular compound or compound class. Independent temperature control helps ensure that all compounds are detected.
How Does ELSD Work?
Sample eluting from a flash cartridge enters the ELSD where it is mixed with compressed nitrogen to nebulizer the sample (creates small droplets). The nebulizer is heated and begins to evaporate the solvent and the nitrogen pushes the sample into a heating chamber where the remaining solvent is evaporated leaving small sample particles in the nitrogen stream.