The rapifleX® MALDI PharmaPulse® accelerates the drug discovery process utilizing label-free mass spectrometry for uHTS.
Unique speed and specificity offered by label-free MALDI-TOF mass spectrometry
Less than a second per sample.
Maximum uptime in 24/7 operation and full automation.
Label-free mass spectrometry for lowest false discovery rates.
Enhancing performance for a wide range of screening applications.
rapifleX® MALDI PharmaPulse®
The all new rapifleX® MALDI Time-of-Flight mass spectrometer is the heart of the MALDI PharmaPulse®, it incorporates Brukers latest 10 kHz scanning laser technology and can read multiple samples per second. All components of the system work in concert for fully automatic HTS operation. The newly designed screening software suite supports HTS workflows and works in combination with a proprietary assay development module which empowers assay developer to accelerate label-free assay development for MALDI mass spectrometry. The latest ‚Synthesis Screening‘ software module of the rapifleX® MPP opens a new application space for e.g. monitoring of chemical reactions at high pace or analysis of binding assays at incomparable high throughput and specificity.
RAPIFLEX MALDI PHARMAPULSE
The use of mass spectrometry allows the measurement of unmodified substrates in primary screens to avoid false positives or false negatives, making confirmation screens redundant. The system is designed for fully automatic handling of 384 and 1536 sample plates to screen more than a million compounds in a week in support of drug discovery.