Study the pharmacological effects of drugs and other vasoactive compounds on small isolated vessels, veins or other vessels under near-physiological conditions.
Acid resistant stainless steel for avoiding lipids sticking
Ideal for pressurized arteries
Direct data streaming to MyoVIEW Live Tracking
Reliable, flexible & trusted
The Pressure Myograph System - 114P is used to measure small arteries, veins, and other vessels physiological function and properties. It allows studying pharmacological effects of drugs and other vasoactive compounds on small isolated vessels under near-physiological conditions. A small, intact segment of an artery or vein is mounted onto two small glass cannulas and pressurized to a suitable transmural pressure. The near-physiological condition permits the investigation of myogenic responses, flow-mediated dilation, and pharmacological agent testing, either to the superfusate or luminal solution.
A built-in heating system maintains the chamber temperature, eliminating the need for continuous and often costly superfusion. The chamber cover includes ports for superfusion, rapid draining and filling, cumulative addition of drugs, and oxygenation. To facilitate cleaning, the chamber is made of acid-resistant stainless steel.