Since 2004, Diagenode has accumulated shearing expertise to design the Bioruptor® Pico and guarantee the best experience with the sample preparation for number of applications -- in various fields of studies including environmental research, toxicology, genomics and epigenomics, cancer research, stem cells and development, neuroscience, clinical applications, agriculture, and many more.
The Bioruptor® Pico is the latest innovation in shearing and represents a new breakthrough as an all-in-one shearing system capable of shearing samples from 150 bp to 1 kb. The shearing accessories and consumables have been developed to allow flexibility in sample volumes (20 µl - 2 ml) and a fast parallel processing of samples (up to 16 samples simultaneously). The built-in cooling system (Bioruptor® Cooler) ensures high precision temperature control. The user-friendly interface has been designed for any researcher, providing an easy and advanced modes that give both beginners and experienced users the right level of control.
In addition, Diagenode provides fully-validated tubes that remain budget-friendly with low operating cost (< 1€/$/DNA sample) and shearing kits for best sample quality.
DNA shearing for Next-Generation-Sequencing
Protein extraction from tissues and cells (also for mass spectrometry)
FFPE DNA extraction
Protein aggregation studies
Best suited for ChIP-seq and NGS sample preparation
Chromatin shearing 200 by - 1kb
DNA shearing 150 by - 1 kb
RNA shearing 200 by - 1 kb
FFPE nucleic acid extraction
Cell lysis and tissue disruption
Mass spectrometry Protein aggregations