leukemia test kit / for hematology / for BCR-ABL mutations / blood
ELITe MGB® RTSG07PLD190

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Characteristics

  • Applications:

    for leukemia, for hematology

  • Tested parameter:

    for BCR-ABL mutations

  • Sample type:

    blood

  • Analysis mode:

    for RT-PCR, for real-time PCR

Description

The product of the Philadelphia translocation, the BCR/ABL oncogene P190 isoform, is commonly found in acute lymphoid leukemia, a rare disease that can be fatal within a matter of months if untreated. Detection and quantification of P190 BCR-ABL fusion gene, by molecular methods, is crucial for patient management, to initiate the appropriate treatment and measure response to therapy.

BCR-ABL P190 ELITe MGB® Kit is a real-time PCR assay for the detection and quantification of the mRNA of the BCR-ABL t(9;22) translocation of the Philadelphia chromosome, isoform P190 compared to the kinase protein Abelson (ABL) mRNA. The assay has been tested on a large range of sample types with conventional extraction and PCR systems.