leukemia test kit / for hematology / for BCR-ABL mutations / blood
ELITe MGB® RTSG07PLD210
for leukemia, for hematology
for BCR-ABL mutations
for RT-PCR, for real-time PCR
The product of the Philadelphia translocation, the BCR/ABL oncogene P210 isoform, is typically found in chronic myelogenous leukemia, and in acute lymphoid and myeloid leukemia, causing the cells to divide uncontrollably and inducing severe outcomes among patients. Detection and quantification of P210 BCR-ABL fusion gene, by molecular methods, is crucial for patient management, to initiate the appropriate treatment, measure the response to therapy and predict relapse
BCR-ABL P210 ELITe MGB® Kit is a real-time PCR assay for the quantification of the mRNA of the BCR-ABL rearrangement, t(9;22) translocation of the Philadelphia chromosome, isoform P210 compared to the mRNA of the gene coding the kinase protein Abelson (ABL) mRNA. The assay has been tested on a large range of sample types with conventional extraction and PCR systems.