cardiovascular disease test kit / cardiac troponin I / latex agglutination / immunoturbidimetric
for cardiovascular diseases
cardiac troponin I
latex agglutination, immunoturbidimetric
Cardiac troponin I is expressed in cardiac muscle tissue by a single isoform with a molecular weight of 23876 Da and consists of 209 amino acid residues. For more than 15 years, troponin I has been known in literature as a reliable marker of cardiac muscle tissue injury and is considered to be more sensitive and significantly more specific in diagnosis of the myocardial infarction than the “golden marker” of the last decades – CKMB.
Published literature states that serum levels of cardiac enzymes and isoenzymes are essential to the diagnosis or exclusion of myocardial damage and that cardiac troponin I is specific for cardiac tissue and is detected in the serum only if myocardial injury has occurred. These reports state that troponin I determination allows early identification and stratification of patients with chest pain suggestive of ischaemia, allows identification of patients that present 48 hours to 6 days after infarction, and identifies patients with false positive elevations in CKMB16.