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  3. Granulator for the pharmaceutical industry
  4. GEA Tiromat Packaging - GEA Food Solutions Germany

Granulator for the pharmaceutical industry FlexStream™
dryerfluidized bed

granulator for the pharmaceutical industry
granulator for the pharmaceutical industry
granulator for the pharmaceutical industry
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Characteristics

Applications
for the pharmaceutical industry
Other characteristics
dryer, fluidized bed

Description

FlexStream™ is a new multi-purpose processor that addresses the current shortfalls of traditional fluid bed processing, including linear scale-up, fully contained loading and unloading for Pharmaceutical applications. Traditional Fluid Bed Technology Fluid bed operations such as drying, granulation or particle coating are often major process steps in the production of solid dosage forms. And, even though the technology has been in use by pharmaceutical companies, globally, for more than 50 years, it has still a lot of shortfalls. Each unit operation needs dedicated machinery or process containers to achieve optimal performance. Another area of concern is scale-up, a task that is often complicated by different bed heights and inconsistencies between fluid bed processors. From a performance standpoint, granules produced by fluid bed granulation often show an excellent compression behaviour but can be weak and flow poorly (compared with high shear granulation). Some formulations can’t be granulated in a fluid bed at all, and coating applications based on conventional Wurster columns are subject to a number of drawbacks, such as scale-up issues, loss of coating material and agglomeration loses.

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.