Granulator for the pharmaceutical industry UltimaPro™

dryerhigh-shear

Flexible technology for standard wet granulation, melt granulation, pelletizing or effervescent production, combined with vacuum or microwave drying Swinging bowl options during vacuum drying results in an improvement of the granule characteristics and a reduction in drying time Easy and efficient cleaning (CIP) Compact technology – reduce space requirement by incorporating several processing steps into one machine A single pot processor is a high-shear mixer-granulator that is also equipped with drying technologies. Thus, single pot processing is the production of pharmaceutical granules using a wet granulation process in which dry mixing, liquid addition, wet granulation, drying and sizing of the granules is done in one machine. By integrating granulating and drying capabilities into a single unit, capital investment in equipment and good manufacturing practice (GMP) floor space is lower than other alternatives. The number of material handling steps is decreased: consequently, the total processing time is shorter while maintaining a high yield and keeping production support to a minimum. At the same time also the number of required operators is reduced. Environmental variables, such as humidity, are eliminated from the manufacturing process, which may offer advantages for processing moisture-sensitive formulations. Requirements for solvent recovery systems are lower for single-pot processors compared with fluid bed dryers. Reaching a high level of containment is easy by application of the correct measures at in- and outlet valves.