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Genetic mutation test kit HepB Typer-Adefovir
hepatitis BHBV

genetic mutation test kit
genetic mutation test kit
genetic mutation test kit
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Characteristics

Applications
for genetic mutations, hepatitis B
Micro-organism
HBV

Description

Detection of Adefovir Resistance in Chronic Hepatitis B Product Overview Chronic hepatitis B can progress to cirrhosis and hepatocellular carcinoma, and the inhibition of the proliferation of the causative hepatitis B virus is clinically important. As the duration of antiviral administration increases, the risk of drug resistance also increases, making long-term inhibition of hepatitis B viral load more difficult. HepB Typer-Adefovir provides a sensitive diagnosis of mutations that cause Adefovir resistance and provides guidelines for the drug regimen of chronic hepatitis B treatment. Features High Accuracy and Sensitivity - Analytical sensitivity: 100 IU/ml - Fully concordant with direct or clonal sequencings Early Detection of Drug Resistant Virus - Detects drug resistant virus of less than 10% of the whole viral population Monitoring of Relative Abundance - Predicts viral breakthrough, the main cause for failure in hepatitis B treatment, by monitoring predominance of resistant virus known to precede viral breakthrough Definitive Determination of Mixture of Multiple Mutations - Precisely identifies mixture of multiple mutations, whereas direct sequencing could not identify specific genotypes with a double mutation in one codon due to the inability of sequencing to determine haplotype

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