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Melanoma test kit MELACAN™
oncologyfor precision medicinefor BRAF mutations

Melanoma test kit - MELACAN™ - Geneseeq - oncology / for precision medicine / for BRAF mutations
Melanoma test kit - MELACAN™ - Geneseeq - oncology / for precision medicine / for BRAF mutations
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Characteristics

Applications
for melanoma
Application field
oncology, for precision medicine
Tested parameter
for BRAF mutations, for NRAS mutations, for MEK mutations, for c-KIT gene mutations
Sample type
plasma, FFPE tissues, liquid biopsy

Description

Melanoma is the most serious type of skin cancer. Treatment for melanoma depends on the size and stage of cancer. While surgical removal may be adequate for early-stage small melanomas, when it spread beyond the skin, chemotherapy, radiation therapy, targeted therapy or immunotherapy may be needed. To date, multiple targeted therapies (e.g. BRAF and MEK inhibitors) and immunotherapies (e.g. PD-1 and CTLA-4 inhibitors) have been approved by FDA to treat advanced melanoma. Detects driver mutations in melanoma such as BRAF, MEK, c-KIT and NRAS to inform targeted therapy options Predicts efficacy and toxicity of chemotherapy based on associated genetic biomarkers Assesses genetic predisposition for melanoma WHO IS IT FOR Melanoma patients seeking precision medicine Patients with unresectable or metastatic melanoma Melanoma patients with recurrent disease SAMPLE TYPES Tumor tissue (FFPE block/slides, or frozen tissue) Fine needle biopsy Liquid biopsy (plasma and others)

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