Melanoma is the most serious type of skin cancer. Treatment for melanoma depends on the size and stage of cancer. While surgical removal may be adequate for early-stage small melanomas, when it spread beyond the skin, chemotherapy, radiation therapy, targeted therapy or immunotherapy may be needed. To date, multiple targeted therapies (e.g. BRAF and MEK inhibitors) and immunotherapies (e.g. PD-1 and CTLA-4 inhibitors) have been approved by FDA to treat advanced melanoma.
Detects driver mutations in melanoma such as BRAF, MEK, c-KIT and NRAS to inform targeted therapy options
Predicts efficacy and toxicity of chemotherapy based on associated genetic biomarkers
Assesses genetic predisposition for melanoma
WHO IS IT FOR
Melanoma patients seeking precision medicine
Patients with unresectable or metastatic melanoma
Melanoma patients with recurrent disease
SAMPLE TYPES
Tumor tissue (FFPE block/slides, or frozen tissue)
Fine needle biopsy
Liquid biopsy (plasma and others)