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Cancer test kit
for BRAF mutationsplasmaurine

cancer test kit
cancer test kit
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for cancers
Tested parameter
for BRAF mutations
Sample type
plasma, urine, tissue
Analysis mode


[Intended use] BRAF gene, located on the 7th chromosome, is a proto-oncogene which encodes a protein belonging to serine / threonine protein kinase raf/mil family. BRAF gene mutations occur in a variety of cancers, including non-Hodgkin's lymphoma, colorectal cancer (10%), malignant melanoma (>60%), thyroid cancer (90%), and non-small cell lung cancer (1-4%). In melanoma patents with BRAF mutations, the therapy effectiveness of Vemurafenib and Dabrafenib is closely associated with the mutation status of the BRAF gene. This kit detects two common mutations of V600E and V600K in the BRAF gene with a total frequency >97% The kits can be used for 1) early screening and early diagnosis of cancer, 2) early monitoring of cancer relapse, and 3) selection of targeted therapy. [Detection principle] This kit uses pyrophosphorolysis activated polymerization (PAP ) technology to specifically amplify the mutant DNA but not wildtype DNA molecules. The amplified product is measured in real time fluorescence format. [Samples] Fresh or frozen tissues, paraffin-embedded tissues, plasma and urine. [Advantages] 1. High sensitivity: ability to detect a single copy of BRAF mutations. 2. High specificity: virtually no false positive amplifications even in the presence of heavy background of wildtype DNA. 3.Freeze-dried format: much earlier and user-friendly manipulation. 4. Non-invasive sampling: plasma and urine samples can be applied.
*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.