Cardiology organ perfusion system IH-9

heartisolated

The IH-9 system is a tabletop isolated heart perfusion system developed for small pigs with a body weight up to about 20 kg. It can also be used for rabbit or mini pig models. The IH-9 offers ultimate perfusion stability and real physiological conditions for longer, more relevant recordings with fewer artifacts. The modular nature of the IH-9 allows the system to evolve along with your research. Our Langendorff system can easily be upgraded to full working heart system. Both Langendorff and working heart modes allow a choice of measurement capabilities with dedicated packages available for specialized applications, such as measurement and analysis of multiple ECG and MAP signals. Perfusion of such larger hearts also creates the opportunity for detailed study of cardioplegia solutions and reperfusion after cardioplegia. Infarct studies with reperfusion and many other studies similar as on smaller hearts are possible. Advanced System Design The IH-9 utilizes the proven architecture and functional principle of our smaller IH-5 system but is engineered for the increased flow produced by these larger species. The system can be operated in any one of the three modes: retrograde Langendorff perfusion under constant pressure, retrograde Langendorff perfusion under constant flow, and real ejecting working heart. The IH-9 allows standard hemodynamic as well as ischemia-reperfusion studies using saline or erythrocyte-containing perfusion solutions or real blood (heparinized). Saline perfusions will not be optimal as the O2 transport in saline solution is not sufficient enough for these large organs.