The N-VivoTM Coronary Calcium Scoring Application is the most precise on the market. Our patented software is capable of finding smaller plaques than any other detection method. Our icon-based system makes measuring and reading results easier than ever before.
Coronary calcium scoring by other methods has exposed several limitations:
- Scores are CT scanner and scan technique dependent. Fixed and arbitrary plaque HU thresholds and multipliers are not calibrated nor are the voxel densities of the plaque.
- The Agatston Score, although valuable in developing coronary artery calcium scoring, has repeatly been shown to produce variable results with precisions too high for optimum therapy monitoring.
- Current manual scoring methods are subjective and operator dependent. Manual scoring is time consuming and tedious, especially so if smaller voxel images are used.
- Scores vary over time from scanner drift, X-ray tube replacements and changes in scan parameters. In addition, although not yet well recognized, the results vary dependent on the patient's physical composition including size, and bone/ muscle/ fat composition.
The methodology of current scoring techniques is too subjective. As a result, scoring algorithms, population reference data, plaque thresholds, and the resulting patient scores vary among different CT manufacturers, over time and between different institutions. Published results report 15% to 40% short-term precision and gross differences in scores between some manufacturers!
Current calcium scoring products provide a fixed plaque threshold based on uncalibrated HU values, typically 85 or 130 HU.