Automated immunoassay analyzer Aptiva®

for clinical diagnosticmultiplexingmagnetic bead-based

Overview
Aptiva® brings Particle-based Multi-Analyte Technology (PMAT) to automated autoimmune diagnostics, enabling simultaneous detection of multiple autoantibodies from a single sample to improve laboratory efficiency and clinical decision support.

Key benefits

• Streamlines lab workflow through simultaneous multi-analyte testing
• Increases diagnostic information by detecting multiple autoantibodies in one run
• Supports risk stratification and faster clinical decision-making

Performance and capacity

• Up to 720 results per hour
• Primary sample capacity: 150 patient tubes with continuous random-access loading
• Consumable walkaway time: up to 6.5 hours
• Reagent carousel: 20 cartridges
• Supports STAT samples and continuous processing with time-to-first and time-to-next sample results

Particle-based Multi-Analyte Technology (PMAT)

• Simultaneous sample reactions for all analytes within each cartridge
• Unique signature assigned to each analyte for multiplex identification
• Solid-phase fluorescence immunoassay quantifies antibody levels

Digital image capture

• Paramagnetic particles are aligned using magnets
• LED illumination enables high-contrast imaging
• Optical system captures high-resolution digital images to distinguish particle signatures
• Images are analyzed to quantify antibody concentrations

Stored raw digital data and result generation

• Aptiva® stores captured digital images and associated raw data in its database
• Results can be generated on demand based on LIS or clinician orders
• Stored images allow retrospective result generation without reprocessing samples or redraws

User interaction and instrument features

• Intuitive icon-driven touchscreen interface
• Cuvette tower designed for replenishment during operation
• Dedicated probes to prevent carryover and improve throughput
• Cuvette dry waste drawer for easy access
• RFID reader records consumable identity for traceability

Technical specifications

• Throughput: up to 720 results per hour
• Primary sample capacity: 150 primary patient tubes (continuous load, random access)
• Consumable walkaway time: up to 6.5 hours
• Reagent capacity: reagent carousel holds 20 cartridges
• Sample handling: supports STAT and continuous processing; time to first/next sample results supported
• Assay technology: PMAT — simultaneous multi-analyte solid-phase fluorescence immunoassay
• Digital capture: high-resolution digital image capture of paramagnetic particles
• Data management: raw digital images stored; results generated on demand via LIS or clinician orders
• Design features: intuitive touchscreen, cuvette tower replenishable during operation, dedicated probes to eliminate carryover, cuvette dry waste drawer, RFID consumable tracking