MAGFLO NGS magnetic beads provide a reliable solution for the purification of nucleic acid fragments with a consistent size distribution, which is crucial for NGS library preparation workflows. This includes both single- and double-sided size selection methods for DNA or RNA, as they are free of RNases.
An advantage of using magnetic beads for NGS size selection is that they allow protocol automation, increasing the reproducibility of results. To automate MAGFLO NGS magnetic bead workflows, we recommend combining the beads with our range of benchtop liquid handling instruments and MAG or HEATMAG modules to provide streamlined, hands-free purification and size selection workflows. This provides an end-to-end solution from a single trusted supplier.
Applications
NGS library clean-up
NGS size selection during library preparation
Magnetic beads are adept at selectively isolating DNA fragments according to their size, a critical step for both single- and double-size selection in NGS library preparation. Employing MAGFLO NGS beads with MAG or HEATMAG modules, combined with the precision offered by INTEGRA's pipetting platforms, for magnetic bead purification ensures high yields while minimizing bead loss.
Single size selection
Left or right size selection of nucleic acid fragments
MAGFLO NGS magnetic beads feature a single magnetic bead-to-sample ratio in single size selection
Double size selection
Left and right size selection of nucleic acid fragments
DNA amplicon sequencing
Library preparation for the Illumina MiSeq™ System
RNA-Seq
Comparative analysis of gene expression patterns in RNA sequencing