Bovine pericardium dural substitute DuraGen® Secure

DuraGen® Secure Dural Regeneration Matrix is a versatile onlay dural graft designed for enhanced contact assurance for patients with compromised dural margins. Overview Enhanced Contact Assurance In challenging cases, keeping the graft in place and ensuring secure contact are critical steps to achieving CSF leak prevention. Cellulose microlayer and 30% denser collagen for enhanced contact with superior handling.1,2 Preventing CSF Leaks with DuraGen Secure Dural Regeneration Matrix DuraGen Secure offers six times greater slip resistance than traditional collagen onlay grafts, even under repeated watertight closure can be achieved. Features CSF Leak Prevention in Challenging Patients For the neurosurgeon, patients with compromised dural margins present a unique challenge. Less than ideal margins create uncertainty about achieving a watertight seal, since good graft-to-margin contact is essential to the fibrin clot formation that closes off pathways where CSF leaks might occur. The Science of DuraGen Secure Dural Regeneration Matrix The unique, fluid activated cellulose microlayer of DuraGen Secure offers six times more slip resistance than traditional collagen onlays. Clinical Over 1,400 patients in 11 Published Clinical Studies 0% Foreign body response 1.9% Infection rate 2.1% Leakage rate Integra's DuraGen products have more published human clinical data than any other collagen-based dural graft (as of 2010) . Clinical studies have shown effective protection against CSF leakage with suture-less closure and no reports of foreign body reactions or graft rejections.