The AccuTOF LC-plus 4G, the third generation of the successful AccuTOF LC series, is a simple, robust and versatile atmospheric pressure ionization high-resolution time-of-flight mass spectrometer (API-HRTOFMS). It can provide solutions for a wide variety of fields with JEOL’s unique ionization technologies, DART and ColdSpray, in addition to the standard electrospray ionization (ESI), the most widely used ionization technique for LC/MS.
The AccuTOF LC-plus 4G is a simple and robust LC/MS system. It offers a wide variety of applications for LC/MS with optional Atmospheric Pressure Chemical Ionization (APCI) source, in addition to the standard orthogonal ESI source. Accurate mass measurements in LC/MS can be made routine by automating the introduction of the internal mass reference compound with the optional Auto-Injection Valve.
DART (Direct Analysis in Real Time)
JEOL, the pioneer of ambient ionization
DART was born in 2003 at the mass spectrometry applications laboratory of JEOL USA, Inc. Among a series of new ionization techniques, which were later termed “ambient ionization,” DART was the first to have been invented and the first to have been commercialized in 2005.
With the optional ColdSpray ion source, thermally labile analytes, including self-assembling supra molecules, some classes of organometallic complexes, short-chain double stranded DNAs, can all be analyzed intact. ColdSpray ionization was developed by Prof. Kentaro Yamaguchi, et al., of Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University (previously Chiba University) and the result of a project funded by the Japan Science and Technology Agency.