Elevated plus experiment maze

Tfor animal researchfor mice

Description Graeff, Viana, and Tomaz (1993) developed the Elevated T-Maze to probe deeper into anxiety disorders. Conditioned fear is associated with generalized anxiety disorder (GAD), and unconditioned fear is linked to panic disorder (PD). The Elevated T-Maze relies on the subjects’ innate fear of heights and open spaces. Anxiety in rodents can be analyzed by evaluating inhibitory avoidance in the face of conflicts whereas panic can be analyzed using one-way escape tests on the Elevated T-Maze. If there are a similar increase and decrease in the tendency to avoid or escape in the elevated T-Maze, then locomotor tests need to be conducted independently to draw any robust conclusions. MazeEngineers offers sizing appropriate for mice and rats.