Animal research organ perfusion system Liver & Kidney Perfusion setups_LF31

for transplantationfor rodentsfor mice

Measuring system for isolated rat kidney or liver The isolated perfused liver and isolated perfused kidney models have been a standard technique for studies in the field of pharmacology since decades. The whole organ perfusion system from MDE Ltd. is a compact and reliable equipment for the adjustment of generally used basic methods on rodents. The MDE isolated liver or kidney perfusion system provides researchers with a versatile and precise tool for studying organ function and pharmacological processes. By allowing the precise manipulation of perfusate composition, this system facilitates investigations into drug metabolism, organ function, and responses to various interventions. The main advantage of the MDE isolated liver and kidney perfusion setups lies in their innovative design and functionality, providing several key benefits: Preservation of Organ Function: The system maintains isolated organ function within a horizontally placed evaporation chamber, preventing deformation of the organ’s vasculature and ensuring optimal functionality. Controlled Perfusion and Temperature: The perfusion pump-controlled flow of buffers and precise temperature control of both perfusion buffer and the evaporation chamber maintain optimal conditions for organ viability and functionality. Sample Collection for Analysis: The relatively low perfusion buffer volume allows for the collection of bile, urine, and organ-passed buffer fractions, facilitating qualitative or quantitative analysis of substances such as drugs, drug metabolites, and hepatic enzymes.