It’s time to revolutionize the rapid freezing process
PrestoCHILL reduces freezing time to 60 seconds and eliminates freezing artifacts through ultrafast freezing, preventing the formation of ice crystals. Cut fatty tissues, like breast or lymph nodes, can be frozen without difficulty and without the distortion of their delicate honeycomb structures.
While using Milestone’s patented “face-down” embedding technique and PrestoCHILL, it is possible to obtain perfectly “flat plane” surfaces to reduce trimming time and cut more easily.
No freezing artifacts
60 seconds freezing time
An all-dry system
Full downloadable documentation
No liquid nitrogen
No Co2 – No isopentane
Pathologists rely heavily on the frozen section technique to provide intraoperative consultations when the surgeon requires a rapid diagnosis or immediate feedback relating to surgical margins. Frozen sections provide a short turnaround time (15-20 minutes) but with the disadvantage of lower diagnostic quality than paraffin sections due to cryoembedding artifacts and variability of staining protocols. A major reason for the lower quality versus a FFPE section is that frozen sections are only stained while FFPE sections are first processed (fixation + dehydration + clearing) and subsequently stained. Quick samples’ freezing and enhanced slide processing staining are necessary for quality diagnosis on intraoperative Frozen Sections.
The freezing is needed to have the surgical sample hard enough to be cut in a thin section mounted on a microscope slide and examined under the microscope. It is the freezing that makes the procedure fast enough to be done during a surgery.