Automatic molecular screening system Monolith series

binding affinityprotein-protein interaction

Directly measure the strength of molecular interactions in solution, without the need for immobilization. Characterize nearly all types of molecular interactions — even the most challenging ones. With ultra-low sample consumption and versatile capabilities, Monolith is the best solution for your binding affinity experiments. Introducing Monolith X with breakthrough Spectral Shift Technology With Monolith X, you’ll get Spectral Shift and MST — two biophysical modalities to help cover all the types of interactions you encounter. You’ll enjoy high-quality results without spending your time on assay development and finally perform experiments without worrying about sample aggregation or impurities. Many great ways to use Monolith Use Monolith as your trusted orthogonal tool to validate binding results or to get a Kd in challenging situations that SPR can’t handle. Monolith works great for countless molecules and buffers so you’re able to tackle the wide variety of projects that come your way. Validate your SPR results with an immobilization-free method It’s common practice to validate your results with more than one technique because you want to be confident that the results are real. Monolith, with its immobilization-free measurement, is the perfect orthogonal tool for SPR users. It removes the immobilization bias and helps to confirm your results, identify false positives, or find binding partners that your primary assay missed.