The Olympus FVMPE-RS multiphoton imaging system is purpose-built for deep imaging in biological tissue, aimed at revealing both detail and dynamics. Innovative features for efficient delivery and detection of photons in scattering media enable high signal-to-noise ratio acquisition. This translates to bright images with precise details — even from deep within the specimen. High sensitivity is matched with high-speed imaging to capture rapid in vivo responses. For advanced applications, dual-wavelength excitation extending to 1300 nm is available. Independent control of visible or multiphoton laser light stimulation and the ability to synchronize with patch clamp data are also possible.
Multiple configurations are available on the FVMPE-RS platform; each imaging system is customizable to meet your unique research requirements.
Maximize Resolution in Deep Imaging
Olympus TruResolution objectives maximize resolution and contrast for 3D imaging deep within thick specimens. The objectives are equipped with a motorized correction collar that can automatically and dynamically compensate for spherical aberration while maintaining focus position.
Refractive index mismatch between the sample and immersion medium introduces spherical aberration that degrades the focus of an objective lens. This aberration worsens deeper into the sample, yielding progressively poorer images with depth. TruResolution objectives solve this challenge with an autocorrection collar. The system can be driven either by an algorithm that finds the best collar setting at each depth or by user-defined manual presets to deliver consistently bright and sharp images through out