Celiac disease test kit CeliacStrip
for DNA

celiac disease test kit
celiac disease test kit
Add to favorites
Compare this product
 

Characteristics

Applications
celiac disease
Sample type
for DNA

Description

Test for the detection of HLA haplotypes associated to celiac disease.CeliacStrip detects the presence or absence of haplotypes that encode HLA-DQ2 and HLA-DQ8.Celiac disease is a chronic inflammatory condition of the intestine that is triggered by the consumption of gluten or associated proteins found in wheat, barley and rye. It is one of the most common conditions affecting the Caucasian population, with a prevalence of between 1:100 and 1:500 in Europe and North America.Susceptibility to gluten sensitivity is to some extent genetically predetermined. In most of the human populations studied, 90-95% of patients were carriers of the heterodimer HLA-DQ2, encoded by alleles DQA1*05 and DQB1*02 in cis position (more common in Central and Northern Europe) or in trans position (more common in Mediterranean countries). The remaining patients (5-10%) often have a second heterodimer, HLA-DQ8 (mainly in indigenous South American patients), encoded by alleles DQA1*03 and DQB1*0302. Patients who are non-carriers of DQ2 or DQ8 may show at least one separate DQ2 allele; very few cases have been described where both alleles are absent.

Catalogs

No catalogs are available for this product.

See all of Operon S.A.‘s catalogs
*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.