Medium reagent PlentiPlex™Mastocytosis

for mutation detection

PlentiPlex™ KIT Mastocytosis qPCR Assay provides a fast and easy evaluation of the presence of the KIT D816V mutation to assist in the diagnosis of Mastocytosis. INTENDED USE OF PLENTIPLEX™ KIT MASTOCYTOSIS PlentiPlex™ Mastocytosis assay is intended for the detection of the KIT D816V mutation, which is among the WHO criteria for the diagnosis of mastocytosis. PlentiPlex™ Mastocytosis Assay utilises PentaBase’s unique DNA chemistry, known as Intercalating Nucleic Acid (INA™), which vastly increases both affinity and specificity of assay oligonucleotides towards the target region compared to assays based on standard DNA chemistries. Advantages of PlentiPlex™ Mastocytosis: The Assay follows WHO criteria Applicable for large biopsies 2 formats (Ready-to-use & Dispense ready) Enables further personalised cancer treatment Highly sensitive aid to diagnosing Mastocytosis If provided with sufficient input of DNA of sufficient quality, PlentiPlex™ Mastocytosis can detect down to 0.01% of KIT D816V mutated gDNA in a background of wild-type gDNA. PlentiPlex™ Mastocytosisis available in two versions; Ready-to-Use for fast and easy low thoughput analyses and Dispense Ready for high throughput applications.