Filling and sealing machine for the pharmaceutical industry BFL 352 /

bottlefor pharmaceutical applicationsfor bottles

Overview
The PLÜMAT BFL 352 / 354 is a Bottle-Fill-Seal (BFS) system with open-door intervention designed for pharmaceutical liquid filling and sealing of PP/PE polyolefin bottles. Available with an automatic bottle-picking station and an integrated bottle buffer, the system supports integrated manufacturing from ISBM/SBM/EXBM to finished polyolefin container, enabling low downtime and reduced cap rejects.

Key features

• BFS system for PP/PE bottles in standard or custom designs
• Automatic bottle-picking station and active buffer to prevent empty-bottle rejects
• Material: medical-grade PP/PE, compliant with European and US Pharmacopeia
• PP bottles sterilizable up to 121°C; option for closed-system, self-collapsible IV containers (depends on design/material)
• Compatible with MFC cap solutions and economical component consumption (hangers, caps)
• Transparent PP option for glass-like clarity

Applications

• Pharmaceutical liquid filling for IV and parenteral containers
• Production lines integrating stretch/extrusion blow molding (ISBM/SBM/EXBM) with filling/sealing
• Lines requiring controlled handling, sterility and process validation

Production process / Integration

• Empty container formation (ISBM/SBM/EXBM) or supplied primary containers
• Automatic bottle picking and buffering
• Filling of active pharmaceutical ingredient/solution
• Capping/sealing (compatible with MFC cap systems)
• Finished filled and sealed polyolefin bottle

Technical specifications

• Denomination: BFL 352 / 354
• System type: PLÜMAT BFL – Bottle-Fill-Seal (BFS) with open-door intervention
• Options: automatic bottle-picking station, bottle buffer system
• Material compatibility: PP/PE medical grade; EUP/USP conform
• Container types: PP/PE polyolefin bottles, standard or customized
• Primary container production: ISBM/SBM/EXBM or separate stretch/extrusion blow molding
• IV container: closed-system & self-collapsible possible (depends on design/material)
• Sterilization: PP bottles up to 121°C
• Throughput: up to 5,000 bph
• Reject handling: buffer system prevents rejects of empty bottles
• Machine lifetime: >20 years