Automated protein analyzer SONICC®

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Find Hidden Crystals Even Those Not Visible by The Eye Discover crystals buried in precipitate or crystals not visible by the naked eye. Don't Miss Hits Detect Sub-Micron Crystals Detect thin crystals, microcrystals <1 μm, and crystals obscured in birefringent LCP. Target the Right Crystals Distinguish Between Protein or Salt Know if your detected crystals are protein or not using integrated UV imaging. Remove the guesswork. SONICC finds protein crystals that other technologies cannot. The ultimate imaging technology in visualizing protein crystals, Second Order Nonlinear Imaging of Chiral Crystals (SONICC) definitively finds crystals buried in precipitate or submicron crystals naked to the eye. Two powerful technologies, Second Harmonic Generation (SHG) and Ultraviolet Two-Photon Excited Fluorescence (UV-TPEF) are combined together in a completely automated imager to quickly image your high throughput crystallization plates and positively identify protein crystals. Crystals appear white against a stark black background, helping you to identify crystals even in murky environments. SONICC can detect extremely thin crystals, microcrystals <1 μm, and crystals obscured in birefringent LCP. Major pharmaceutical and academic research labs worldwide find SONICC to be extremely successful, cost-effective, and efficient. Find Hidden Crystals That You May Have Missed Before The unique imaging properties of SONICC allow crystal detection in almost any optical environment, including opaque and turbid environments. Only chiral crystals, such as proteins, produce a signal using second harmonic generation (SHG).