New quality in determination of Total Iron-Binding Capacity (TIBC)
• Reduce the time associated with the assay
• Determination can be conducted in a single vessel and in a relatively short period of time
• Reduce sample manipulation steps
• Set can be applied to any automated chemical analyzers
Total iron-binding capacity indicates the maximum amount of iron necessary to saturate all available transferrin iron-binding sites. Therefore, TIBC correlates well with transferrin concentration. Measurements of TIBC, serum iron, and the ratio of serum iron to TIBC (transferrin saturation) are widely used for the clinical diagnosis and monitoring of treatment for iron-deficiency anemia and chronic inflammatory diseases as well as for screening tests for other clinical goals. Methods of TIBC determination: calculated TIBC, indirect, direct.