Oral syringe Sympfiny®

Multiparticulate dosage forms: advantages in pediatric drug delivery Commonly, drugs for pediatric patients are administered orally as liquids, rapid dissolve tablets or chewable tablets. The problem: poor tasting drugs are a major cause of incomplete dosing in childrentaste masking bitter drugs often relies on the use of sugar and flavoringsthere can be dosing inaccuracies with liquid medication for small dosing volumes Multiparticulate drugs for direct oral delivery consist of tiny granules or spheres providing many advantages that address the challenges in pediatric drug delivery: high dosing flexibilityadministration with or without liquideasier to swallow than tablets or capsulestasteless formulations Challenges in the administration of multiparticulate drugs Multiparticulates have properties of both liquid and solid substances. They flow more easily than water and can pour out of small openings. Compressed, as solid particles they “lock” together. Multiparticulates can stick together if they become damp or statically charged. Solutions for liquid dosing are therefore not adequate for multiparticulate drug delivery. Other existing delivery methods are limited to single dose or require complicated preparation steps. The SympfinyⓇ system is a first of a kind innovation specialised in the delivery of multiparticulates. The system of oral syringe and container allows controlled and precise dosage and ensures that an untrained caregiver can dispense the medication directly and accurately into the patient’s mouth.