DETECTION OF TOTAL ANTIBODIES AGAINST LEGIONELLA PNEUMOPHILA SEROGROUPS 1-6 BY IMMUNOFLUORESCENCE
Maximum testing accuracydue to specific conjugate antibodies
Easy visual detectionof indirect immunofluorescence reaction
Reagents can be used under Screening or Titration protocols
High throughput allowed by rapid testing procedure
Procedure amenable to automation
Legionella pneumophila is a gram negative Bacillus, causative agent of Legionnaires’ desease. The clinical symptoms may vary from sub-clinical forms to fatal pneumonia, characterised by a mortality rate of 20% with regards to community infections and of 40% for nosocomial infections.
The Legionellaceae family is nowadays composed by over 50 Legionella species divided into 70 serogroups, of which the most relevant is serogroup 1, being it responsible for most Legionella infection cases.
The Legionella pneumophila sg. 1-6 IFA kit allows rapid serological confirmation of samples upon detection of specific antigen in urine. The rapidity of diagnosis confirmation may significantly contribute to reducing mortality. Furthermore, the additional indication of the actual infection stage (acute or convalescent) is obtained by means of using the kit under the directions of the Titration Protocol.