The LCMS-8040 is a step further from the technology provided by The LCMS-8030 in terms of sensitivity. Shimadzus UFsweeper™ collision cell technology enables superfast MRM transition speeds, around 555 MRMs per second. This device is also known for its quick polarity switching feature. Apart from the collision cell technology, the enhanced ion optics feature offers higher multiple reaction monitoring (MRM) sensitivity. The device has achieved a five-fold improvement in its sensitivity ratio by improving ion focusing feature and by reducing the ion losses incurred by multi-pole lenses.