Intended use
In vitro quantitative determination of the concentration of serum amyloid A in human serum, human plasma, and human whole blood samples.
Summary
SAA is a human acute phase protein, which is a normal component present at low levels in the blood. It rises quickly when the human body has bacterial or viral infectious inflammation, active disease, or large-scale tissue damage. In the acute phase of inflammation or infection ( 48h~72h) can increase rapidly, and decrease rapidly during the recovery period of the disease. Studies have shown that elevated serum SAA can be detected in diseases such as bacteria, fungi, viral infections, atherosclerosis, cardiovascular disease, and acute transplant rejection. Similar to C-reactive protein, SAA helps diagnose inflammation and evaluate its therapeutic effects. However, in some diseases, such as viral infections, cardiovascular diseases, transplant rejection, etc., SAA can be more sensitive than C-reactive protein, and can be Clinical diagnosis provides better reference value. Combined detection of C-reactive protein and SAA can improve the sensitivity of the diagnosis of infection.
Commonly used detection methods include immunoturbidimetric method, enzyme-linked immunosorbent assay, immunofluorescence chromatography, chemiluminescence method, etc.