automatic sample preparation system / laboratory / dilution / weighing
TPW

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Characteristics

  • Operation:

    automatic

  • Applications:

    laboratory

  • Preparation type:

    dilution, weighing, filtration, by extraction

  • Configuration:

    benchtop

  • Preparation format:

    for tubes

Description

The TPW Automated Sample Preparation Workstation enhances laboratory productivity by minimizing resource allocation for repetitive tasks such as sample weighing, extraction, filtration, dilution, and transfer to analysis devices. This enables the re-purposing of lab staff to mission critical tasks such as data analysis, reporting, and notebook documentation. Automated procedures can also reduce solvent usage and hazardous waste generation while improving analyst safety by minimizing exposure to hazardous reagents and samples.

Assay and content/blend uniformity for up to 100 samples
20 – 520 mL initial extraction volume
Waters Empower™ Interface
Powerful dEsign™ variables for streamlined DoE studies

Extraction
After weighing the sample, the TPW uses a high-shear homogenizer to provide a consistent wet grinding process to quickly extract samples. With this tool, the TPW can achieve efficient and reproducible extraction for even the most challenging dosage forms. Common sample types include traditional solid oral dosage forms including tamper-resistant products, osmotic pump, modified/extended and delayed release formulations. Cleaning between samples is easily programmed into the method to eliminate sample carry-over. The updated TPW is enhanced to reduce cycle times by adding efficiency to the clean-up and dilution processes.

Filtration and dilution
Consistent volumetric preparations are confirmed gravimetrically at every step throughout the process. The TPW uses a fluid metering pump to filter extracted samples as they are transferred from the extraction vessel to processing tubes.