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PCR reagent kit SPG-EGFR001
solutiondiagnostictissue

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Characteristics

Type: solution
Applications: diagnostic, tissue, FFPE tissues, pathology, blood sample, for lung cancer, sample preparation, for PCR, for DNA extraction, for qPCR, for nucleic acids, for DNA purification, for mutation detection, RT-qPCR, for RT-PCR
Format: liquid
Tested parameter: for EGFR mutations
Origin: human-based
Other characteristics: high-sensitivity

Description

Product Name： K-ras Gene Mutations Detection Kit Pack Size：10 Tests/Kit Instruments Validated：Stratagene Mx3000P™,ABI7500,Biorad CFX96 Sample Type:Tumor tissue，Peripheral blood，Pleural and ascites DETECTED GENES 1.G12D 2.G12A 9.Q61L，Q61R，Q61H，A59T，Q61K，A146T，A146V，A146P 3. G12V 4. G12S 5. G12R 6. G12C 7. G13D 8.G13C,G13S,G13R,K117N,K117N 9.Q61L，Q61R，Q61H，A59T，Q61K，A146T，A146V，A146P DETECTION SIGNIFICANCE 1. It is recommended to detect KRAS gene status before systemic treatment for patients with inoperable stage III and IV NSCLC to guide the treatments according to molecular classification. If tissue samples are not available, circulating tumor DNA can be considered for testing. 2. It is recommended to detect KRAS gene status for the potentially resectable group of metastatic colorectal cancer before neoadjuvant chemotherapy or systemic treatment in the palliative care group. The mutation patients are resistant to Cetuximab, Panitumumab and Anti-HER-2 therapies.

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