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PCR reagent kit SPG-KRAS005
solutiondiagnosticfor scientific research

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Characteristics

Type: solution
Applications: diagnostic, for scientific research, tissue, pathology, blood sample, sample preparation, for DNA sequencing, for PCR, for DNA extraction, for qPCR, for mutation detection, for nucleic acids, for RNA extraction, for colorectal cancer, for RT-PCR, RT-qPCR, for lung cancer
Format: liquid
Tested parameter: for KRAS mutations
Origin: human-based
Other characteristics: high-sensitivity

Description

Product Name：K-ras Gene Mutations Detection Kit Pack Size：10 Tests/Kit Instruments Validated：Stratagene Mx3000P™,Biorad CFX96，ABI7500 etc Sample Type：Tumor tissue，Peripheral blood，Pleural and ascites DETECTED GENES 1.G12D 2.G12A 3.G12V 4.G12S 5.G12R 6.G12C 7.G13D 8.G13C,G13S,G13R,K117N,K117N 9.Q61L,Q61R,Q61H,Q61H 10.A59T,Q61K 11.A146T,A146V,A146P DETECTION SIGNIFICANCE 1. It is recommended to detect KRAS gene status before systemic treatment for patients with inoperable stage III and IV NSCLC to guide the treatments according to molecular classification. If tissue samples are not available, circulating tumor DNA can be considered for testing. 2. It is recommended to detect KRAS gene status for the potentially resectable group of metastatic colorectal cancer before neoadjuvant chemotherapy or systemic treatment in the palliative care group. The mutation patients are resistant to Cetuximab, Panitumumab and Anti-HER-2 therapies.

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