Swift Hybridization Capture Kits, enable enrichment and sequencing of the human exome or subsets of disease-related genes involved in cancer and inherited diseases. Our kits save sequencing costs by targeting only genes of interest using a 4-hour capture, while delivering the breadth and depth of coverage required for comprehensive yet sensitive genomic profiling.
The high quality of Swift panels, combined with optimized hybridization reagents and protocols, results in a substantial improvement in on-target mapping rate and coverage uniformity compared to other commercially available panels. The panels are designed to allow variants to be called using fewer reads, and therefore, at lower costs.
These products include gene-specific capture probes and supporting hybridization and wash reagents, including beads and blockers. When used in conjunction with Swift’s portfolio of library preparation kits including library adapters with molecular identifiers, labs have a variety of complete workflow options to convert input DNA into targeted Illumina®-compatible libraries in a 1.5-day workflow.
Highlights
Enables enrichment of the human exome or subsets of disease-related genes
Superior on-target performance and comprehensive coverage of human coding sequences from the RefSeq database, probes designed to version hg19
Saves sequencing costs
Pre-capture multiplexing facilitates orders of magnitude more efficient next generation sequencing by targeting genes of interest while conserving enrichment reagents
Provides high quality data